Which test incorporates maternal age, weight, race, and number of fetuses?

The quad screen is a maternal serum screening test that assesses the risk for certain fetal conditions, including Down syndrome and neural tube defects. It measures four specific markers in the maternal blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), estriol, and inhibin A.

What sets the quad screen apart is its incorporation of various maternal factors to refine the risk assessment. Maternal age is a crucial factor due to its strong association with chromosomal abnormalities. Maternal weight is considered because it can influence the levels of the markers being measured. Race can play a role in baseline levels of certain markers, and the number of fetuses is also relevant, as multiple gestations can alter the expected levels of these markers.

By factoring in these variables, the quad screen provides a more personalized risk assessment, enhancing its predictive value and allowing healthcare providers to better counsel patients on the potential for specific fetal conditions. This comprehensive approach is essential for informed decision-making regarding further diagnostic testing and management during pregnancy.