Which of the following conditions is associated with symptoms of Marfan syndrome?

Prepare for the American Board of Genetic Counseling Test. Engage with flashcards and multiple choice questions, each question comes with hints and explanations to enhance your knowledge. Get exam ready!

Marfan syndrome is a genetic disorder that affects the connective tissue in the body, leading to various symptoms, especially involving the cardiovascular, skeletal, and ocular systems. Loeys-Dietz syndrome is a condition that also involves connective tissue and shares many phenotypic characteristics with Marfan syndrome. Both conditions can lead to cardiovascular complications, including aortic dilation and dissection, and exhibit similar skeletal features such as long limbs and an increased height.

Because Loeys-Dietz syndrome has overlapping features with Marfan syndrome, identifying it as a related condition helps to differentiate it from other disorders listed. While conditions like MEN2B, cardiomyopathy, and Huntington disease may have their own unique symptoms, they do not share the classic manifestations of Marfan syndrome as closely as Loeys-Dietz syndrome does. This makes Loeys-Dietz syndrome the correct answer. The understanding of these overlapping symptoms is crucial for genetic counselors, as it informs risk assessment and management for individuals and families affected by these conditions.

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