What percentage of translocations are typically inherited?

Prepare for the American Board of Genetic Counseling Test. Engage with flashcards and multiple choice questions, each question comes with hints and explanations to enhance your knowledge. Get exam ready!

The correct response indicates that approximately 70% of translocations are inherited. This is significant within genetics, as it highlights the mechanism through which genetic information may be passed from one generation to another, impacting offspring phenotypes and potential genetic disorders.

Translocations occur when segments of chromosomes break off and attach to different chromosomes. They can occur during gamete formation (meiosis) and can be passed on to the next generation. When considering the inheritance of these translocations, certain studies and genetic surveys suggest that a substantial percentage, about 70%, do indeed come from parental genetic contributions.

Understanding the inheritance of translocations is crucial for genetic counselors, as it provides insight into the risks of congenital conditions and the possible need for further genetic testing in families with a history of chromosomal abnormalities. This knowledge helps in developing appropriate management strategies for affected families and tailoring reproductive options.

In terms of the other options, lower percentages do not adequately reflect the data on inherited translocations. While each of those figures — 30%, 50%, and 90% — may encompass unique circumstances regarding specific types of chromosomes or conditions, the consensus around the typical inheritance rate for translocations leans towards the 70% figure, making it the most accurate choice in this context.

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