What is the estimated percentage of all pregnancies that result in miscarriage?

The estimated percentage of all pregnancies that result in miscarriage is approximately 20%. This statistic is noteworthy because it encompasses a wide range of pregnancies, including very early losses, which often go unrecognized. Historically, it has been understood that about 10-20% of clinically recognized pregnancies result in miscarriage; however, when accounting for all pregnancies, including those that occur before clinical detection (e.g., before a missed period), the figure can increase significantly.

Miscarriages are especially common in the first trimester, which is a critical period for fetal development. Various factors contribute to the risk of miscarriage, including chromosomal abnormalities, maternal age, and underlying health conditions. Understanding that around 20% of all pregnancies end in miscarriage helps healthcare professionals and patients normalize and address the complexities surrounding early pregnancy losses. This knowledge is vital for genetic counselors who provide support and information to individuals experiencing pregnancy loss.