What is a key feature of reciprocal translocation?

Prepare for the American Board of Genetic Counseling Test. Engage with flashcards and multiple choice questions, each question comes with hints and explanations to enhance your knowledge. Get exam ready!

Reciprocal translocation is characterized by the exchange of segments between two non-homologous chromosomes. A key feature of this process is that, during segregation, viable gametes can be produced even if individuals may have a translocation. This allows for the possibility of normal gametes alongside those that carry the translocation, which means that offspring may inherit either the normal chromosome arrangement or the one that includes the translocated segment.

The presence of a reciprocal translocation does not necessarily prevent the formation of viable gametes, although individuals may experience some level of reproductive risk and may have reduced fertility. However, not all gametes produced will be unviable, meaning that individuals with a translocation can still have children.

The other options presented do not accurately describe the key feature of reciprocal translocation. For instance, both chromosomes during a reciprocal translocation do not retain their original arms as segments are exchanged. The notion that only one chromosome is involved contradicts the very definition of reciprocal translocation, which involves two chromosomes. Lastly, while certain combinations of translocations may increase the risk of specific disorders, including Down syndrome, reciprocal translocation is not limited to causing just this condition, as various genetic disorders can arise depending on which chromosomes are involved and how

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