What are common symptoms of Primary Ciliary Dyskinesia?

Primary Ciliary Dyskinesia (PCD) is a genetic disorder characterized by the dysfunction of cilia, the tiny hair-like structures that line the respiratory tract and other organs. One of the hallmark symptoms of PCD is chronic respiratory infections. The cilia are responsible for clearing mucus and pathogens from the respiratory system. When they do not function correctly, mucus accumulates, leading to persistent inflammation and recurrent lung infections.

Patients with PCD typically experience symptoms such as chronic cough, wheezing, and sinusitis due to their impaired ability to clear respiratory secretions. This results in an increased risk of bacterial infections in the lungs and sinuses, ultimately causing complications like bronchiectasis if left untreated.

While the other options do address various medical issues, they are not characteristic of PCD. Chronic cardiovascular complications are not directly associated with this disorder. Learning disabilities can occur in some genetic disorders but are not typical symptoms of PCD itself. Severe dermatological issues do not play a role in the presentation of Primary Ciliary Dyskinesia either. Thus, chronic respiratory infections stand out as the most prominent and common symptom of this condition.