Low levels of inhibin A indicate which condition?

Low levels of inhibin A are primarily associated with Trisomy 18, also known as Edwards syndrome. Inhibin A is a protein that is produced by the placenta and is often measured in conjunction with other markers during pregnancy screening for chromosomal abnormalities.

In the context of Trisomy 18, studies have demonstrated that inhibin A levels are typically lower than normal. This abnormality can help flag the potential presence of this condition when combined with other factors in testing, such as maternal age and other markers in prenatal screening.

Inhibin A levels are generally elevated in normal pregnancies, particularly during the second trimester, and they can also show increased levels in conditions like Trisomy 21, making it an important marker to distinguish between various chromosomal abnormalities during screenings. Turner's syndrome may present with normal or slightly altered inhibin A levels, but it is not specifically linked to low levels as Trisomy 18 is. Thus, the association of low inhibin A levels specifically points toward Trisomy 18.