In Androgen Insensitivity Syndrome, what type of inheritance is observed?

Androgen Insensitivity Syndrome (AIS) is indeed classified as an X-linked recessive condition. This means that the gene responsible for this syndrome is located on the X chromosome. In individuals with AIS, the body is unable to respond to androgens, which are male hormones that play a significant role in the development of male physical characteristics.

Since the gene causing AIS is on the X chromosome, males, who have one X and one Y chromosome, will express the condition if they inherit the affected X chromosome. Females, on the other hand, have two X chromosomes, so they would typically require two copies of the mutated gene to express the syndrome, although they can be carriers with one affected allele.

This pattern of inheritance explains why AIS occurs more frequently in males, as they will present with the condition if they inherit the affected X chromosome, while females may simply be carriers unless they inherit the mutated gene from both parents. The characteristics and implications of X-linked inheritance also highlight the distinct mechanisms through which genetic conditions can be passed down and expressed in different sexes.